Contraindications
- Serious immune deficiency
- Malignant disease
- Treatment with beta-blockers, even those administered locally (drops)
- Severe asthma uncontrolled by drug treatment (FEV1 <=70% of predicted, even after drug treatment)
- Non-compliant patient
Relative contraindications
- Children under 5 years of age
- During pregnancy (for the progression phase of therapy)