Cell surface receptor
Many biological mediators which carry information between different cells do so by binding receptors expressed on the surface of the target cell (rather like how a letter ends up at the address specified on the envelope). The binding of a mediator to its cell surface receptor triggers an intracellular signal which leads to a specific response on the part of the target cell. In an allergic reaction, the binding of allergen molecules to corresponding antibodies on the surface of mast cells induces these cells to degranulate, i.e. to empty the contents of their intracellular granules into the extra cellular environment.
To topClinical history (also referred to as anamnesis)
All the information about the disease provided by the patient (or family and friends) to the physician during the interview.
To topConjunctivitis
Inflammation of the conjunctiva of the eye ("red-eye").
To topCorticosteroid
A hormone normally produced by the adrenal glands with potent anti-inflammatory activity. Some synthetically produced corticosteroids are used as medicinal products, e.g. cortisone.
To topCromoglicate
Anti-allergic drug used in ophthalmology and for the prevention of asthma attacks as it inhibits the release of certain inflammatory mediators including histamine.
To topCromoglicate (cromolyn)
An anti-allergic agent, used in ophthalmology, for the prevention of asthma attacks, by preventing the release of certain inflammatory mediators such as histamine.
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