Subcutaneous treatments

Prescribed by an allergy specialist, injections are administered in a medically controlled environment and followed by an observation period of 30 minutes. These pain-free injections are given in order to administer the allergen subcutaneously (under the skin) on the arm between the elbow and shoulder.

Initiation and maintenance phase

• The first phase called "initial treatment" aims at administering increasing doses of allergenic extract to the patient. During the first weeks of treatment, starting with a very low dose of the allergen in question, the dose of the product administered is increased until it reaches the maximum dose the best tolerated by the patient.

• The second phase, called the “maintenance phase” can then start. The maximum tolerated dose at the end of the first phase is then administered at regular intervals (depending on the administration route and the sensitivity of the patient) during a period of time that varies between 3 to 5 years.

Indications

• Allergic disease whose mechanism of sensitisation is IgE-dépendant and where the allergen(s) has/have been identified ;
• Marked clinical discomfort requiring daily symptomatic treatment for long periods ;
• Symptomatic treatments that are either partially effective or causing adverse events ;
• Allergenic eviction methods that are either difficult to implement or are ineffective ;
• Rhinitis and/or potentially severe asthma or likely to worsen in the mid to long term ;
• Motivated and compliant patient ;
• Adults and children (> 5 years).

Contra-indications

• Hypersensitivity to one of the excipients (see list of excipients) ;
• Auto-immune diseases,  immune complex disease, immunodeficiency ;
• Malignant disease or tumour ;
• Severe or poorly controlled asthma (FEVI ≤ 70%) ;
• Patient currently taking beta blockers (including local treatments e.g. eye drops) ;
• Renal failure.